Ranking first on the list of the largest software companies in Japan by market cap is M3 Inc, a firm that primarily provides services centered on the healthcare platform. It is a one-of-a-kind startup firm that runs numerous worldwide services centered around its physician platform, such as m3.com. M3 is the firm founded in 2000, it is listed on the Tokyo Stock Exchange (joining the NIKKEI 225 in 2019). Its 290,000+ Japanese and six million+ global physician member panel serves as the main platform for advancing healthcare innovation and reform across healthcare worldwide. “Making use of the Internet to increase, as much as possible, the number of people who can live longer and healthier lives, and to reduce, as much as possible, the amount of unnecessary medical costs”, is both the desire and goal of M3.

The company is divided into five main segments. Medical Platforms operates marketing-related businesses in Japan through the Internet and real-world operations centered on the medical employee specialized site m3.com. Evidence Solution is involved in the contract research organization (CRO) business, which supports clinical development work and research, as well as the site management organization (SMO) business, which manages clinical trial operations. Career Solutions provides human resource services to healthcare professionals. The Site Solution segment offers operational support to healthcare facilities and home-visit nursing services. The overseas segment offers medical marketing support, research, and career opportunities through medical personnel specialty sites in the United States, China, Korea, India, France, Germany and Spain.

Founded: 2000

Headquarters: Tokyo, Japan

Website: https://corporate.m3.com/

Oracle Corporation Japan develops and sells software and hardware products and solutions in Japan. The company was founded in 1985 and is headquartered in Tokyo, Japan. Oracle Corporation Japan is a subsidiary of Oracle Japan Holding Inc. It offers services to the automotive, communications, construction, engineering, consumer products, research and education, financial sectors, food and beverages, healthcare, technology, hospitality, manufacturing, life sciences, entertainment and media, public sector, retail, and utility industries.

The business is divided into three divisions: Cloud and License, Hardware Systems, and Services. It sells software solutions such as relational database management software, middleware, and applications; hardware such as servers, storage devices, and network devices used in the building and running of IT environments such as cloud computing environments; and cloud services via the Internet and other networks, as well as software license update rights and technical support. In addition, the firm provides hardware technical support, maintenance, and repair, as well as consulting, customer support, and education services.

Founded: 1985
Headquarters: Tokyo, Japan
Website: https://www.oracle.com/

Trend Micro, the next name on the list of the largest software companies in Japan by market cap, is a worldwide cybersecurity leader and contributes to making the world secure for digital information exchange. Its cybersecurity platform protects 500,000+ organizations and 250+ million individuals across clouds, networks, devices, and endpoints, and is powered by decades of security expertise, global threat research, and continuous innovation. Being a leader in cloud and enterprise cybersecurity, its platform provides centralized visibility for better, faster detection and response, as well as a comprehensive set of advanced threat defense techniques optimized for environments, like AWS, Microsoft, and Google.

Trend Micro Research regularly analyzes the threat landscape, gathering the most recent threat intelligence from across the world, to deliver clients the trusted insights they need to withstand threats now and in the future. Businesses may use a cybersecurity platform to consolidate visibility, analysis, and controls across security layers and workflows. As a result, security effectiveness, operational efficiency, and company performance improve. The Trend One platform distinguishes itself by providing enterprise attack surface coverage and providing across the attack protection cycle - responding to attacks and mitigating cyber risks.

Founded: 1988

Headquarters: Tokyo, Japan
Website: https://www.trendmicro.com/en_vn/business.html

SCSK Corporation is a Japanese information technology firm based in Tokyo that provides IT services and computer software. Outside of Japan, it is most known for its 1984 acquisition of Sega, which resulted in the sale to Sammy in 2004, establishing Sega Sammy Holdings. The SCSK Group provides its know-how and various IT solutions it has amassed over the years in addressing the issues of clients and society. Since 1989, the firm has been listed on the Tokyo Stock Exchange under the name Sumitomo Computer Service Corporation.

In Japan, the company provides system integration, cloud computing, information security, and computer software to businesses, mostly on a B2B basis. SCSK Corporation's business type and scope are comparable to that of Itochu Techno-Solutions, Uniadex, and Mitsui Knowledge Industry, all of whom specialize in IT services. Its specialists are knowledgeable in problem-solving across all industries gather and coordinate their experience to provide clients with the best solutions. The company has been providing the full line-up of IT services necessary for business for fifty years, resolving client issues at over 8,000 companies.

Founded: 1968
Headquarters: Tokyo, Japan

Website: https://www.scsk.jp/

Being a market leader for AI IoT Big Data Platforms since its establishment in 2000, it would be missed if not listed the name of OPTiM in the list of the largest software companies in Japan by market cap. OPTiM is a company that focused on developing universal technology, services, and business models. With the slogan "We make the Internet as simple as breathing", OPTiM's mission is to change the situation in which certain IT literacy is still required to use the Internet as an indispensable infrastructure, and to make the Internet itself as simple as breathing that you do not even notice using it. The company has been inventing solutions that allow everyone to experience the creativity and convenience that the Internet provides since its inception.

OPTiM focuses on a single segment for license sales and maintenance support service (Optimal Business), and it offers a wide range of services such as IoT Platform Service, Remote Management Service, Support Service, and other unique services. For consumer customers, it offers "Unlimited Software powered by OPTiM", which allows you to use as much software and e-books as you like for a fixed price. "Unlimited Business Software powered by OPTiM" offers antivirus software and office-compatible software at a fixed fee for business customers. The company also provides Optimal Guard as a security management solution for both consumer and business users to avoid spoofing and information leakage by identifying, stopping, and deleting malicious executable files.

Founded: 2000

Headquarters: Tokyo, Japan
Website: https://www.optim.com/