Johnson & Johnson (J&J) is an American global conglomerate that was founded in 1886 and manufactures medical devices, medicines, and consumer packaged goods. J&J is one of the most valuable firms in the world, and it is one of just two U.S.-based companies with a prime credit rating of AAA, which is higher than the US government.

The headquarter of Johnson & Johnson is in New Brunswick, New Jersey. The firm has around 250 subsidiary companies with activities in 60 countries and products marketed in more than 175 countries. During the fiscal year 2020, Johnson & Johnson had global sales of $82.6 billion.

J&J is well-known for its baby and skin-care products. Immunology, neurology, infectious illnesses, and cancer are the four key areas in which the organization invests. Band-Aid Brand bandages, Tylenol pharmaceuticals, Johnson's Baby products, Neutrogena skin and beauty products, Clean & Clear face cleanser, and Acuvue contact lenses are among its well-known consumer items. Janssen Pharmaceutica is Johnson & Johnson's pharmaceutical division.

• Headquarter: New Brunswick, New Jersey, U.S.
• Founded: 1886 by Robert Wood Johnson, Jame Wood Johnson, Edward Mead Johnson
• Revenue: $82.6 billion (2020)
• Website: https://www.jnj.com/

F. Hoffmann-La Roche AG, also known as Roche, is a Swiss global healthcare corporation with two divisions: pharmaceuticals and diagnostics. The company's headquarters are in Basel. Roche is the world's largest pharmaceutical firm and the world's leading producer of cancer therapies.

Roche is one of the few corporations that raises its dividend every year, with 2020 marking the 34th consecutive year. The European Federation of Pharmaceutical Industries and Associations has accepted F. Hoffmann-La Roche as a full member (EFPIA).

Roche's sales in fiscal 2020 were $63.94 billion.

Roche's best-selling drugs include the multiple sclerosis drug Ocrevus, the hemophilia drug Hemlibra and the cancer drugs Tecentriq and Perjeta.

• Headquarter: Basel, Switzerland
• Founded: 1896 by Fritz Hoffmann-La Roche
• Revenue: $63.94 billion (2020)
• Website: http://www.roche.com/

Bayer AG is a German multinational pharmaceutical and life sciences company and one of the world's major pharmaceutical corporations. Human and veterinary medications, consumer healthcare items, agricultural chemicals, seeds, and biotechnology products are all part of Bayer's business.

Some other outstanding products of Bayer: birth control pill Yasmin, liver cancer drug Nexavar, the drug to prevent recurrence of multiple sclerosis Betaseron,...

• Headquarter: Leverkusen, North Rhine-Westphalia, Germany
• Founded: 1863 by Friedrich Bayer
• Revenue: $51 billion (2020)
• Website: http://www.bayer.com/

Novartis International AG is a Swiss-American global pharmaceutical firm with headquarters in Basel, Switzerland, and Cambridge, Massachusetts, in the United States. It is one of the world's major pharmaceutical corporations.

Novartis is an active member of the European Federation of Pharmaceutical Industries and Associations (EFPIA), the International Federation of Pharmaceutical Manufacturers and Associations (IFPMA), and the Pharmaceutical Research and Manufacturers of America (PhRMA).

Novartis businesses operate across 3 divisions: pharmaceuticals, Alcon (eye care), and Sandoz (generics).
Sandoz is a subsidiary of Novartis AG known for its production of active pharmaceutical ingredients and generic drugs, and Alcon is the division of surgical systems, contact lenses, and ophthalmic drugs. Pharmaceuticals is the largest division of the company, specializing in the production of drugs for cancer, HBP, and many other diseases.

Some prominent products: Clozapine antipsychotic drug, Carbamazepine drug for epilepsy, Imatinib mesylate drug used for chronic myeloid leukemia,...

• Headquarter: Basel, Switzerland
• Founded: 1996 by Johann Rudolf, Alexander Clavel
• Revenue: $49.89 billion (2020)
• Website: https://www.novartis.com/

Merck & Co., Inc. is a worldwide pharmaceutical corporation based in Kenilworth, New Jersey.

Merck develops and manufactures pharmaceuticals, vaccines, biological treatments, and animal health products. Cancer immunotherapy, anti-diabetic medicine, and vaccinations against HPV and chickenpox are among the blockbuster pharmaceuticals or products with 2020 sales.

Based on 2020 sales, the company is rated 69th on the 2021 Fortune 500 and 92nd on the 2021 Forbes Global 2000.

Featured products: Januvia drug for type 2 diabetes, Zetia drug for hypercholesterolemia, Isentress for HIV treatment, Keytruda drug for an immunomodulator, and cancer treatment,...

• Headquarter: Kenilworth, New Jersey, United States
• Founded: 1891 by Theodore Weicker, George Merck
• Revenue: $47.99 billion (2020)
• Website: http://merck.com/

GlaxoSmithKline plc (GSK) is a British multinational pharmaceutical corporation headquartered in London, England, formed through the merger of Glaxo Wellcome and SmithKline Beecham in 2000. According to Forbes, GSK was the world's sixth-largest pharmaceutical firm in 2019.

The company is famous for its products in dermatology, dentistry, neurology, cardiology, especially respiratory. In addition, the company also researches and produces antiviral drugs and vaccines.

Some of the featured products: Advair for asthma, Lamictal for epilepsy, Lovaza for blood cholesterol control, Aquafresh toothbrush, and other dental products are also key products of the GSK.

• Headquarter: 980 Great West Road, London, UK
• Founded: 2000
• Revenue: $46.8 billion (2020)
• Website: https://www.gsk.com/

AbbVie is a publicly listed biopharmaceutical company based in the United States that was created in 2013. It began as a spin-off from Abbott Laboratories.

The company specializes in the research, production, and development of pharmaceuticals in the fields of HIV, hepatitis C, autoimmune diseases, and some other diseases. The company has 7 drug production facilities and distributes to more than 170 countries around the world.

With more than 47,000 professionals and the successful acquisition of Allergan (an American pharmaceutical company) in May 2019, AbbVie strengthens the company's position in several therapeutic areas including immunology, oncology, and neuroscience.

In 2019, the company's revenue increased 2% with significant achievements in the medical and philanthropic side.

Some products stand out: Norvir & Kaletra HIV drug; AndroGel low testosterone drug; TriCor, Niaspan & Trilipix high blood cholesterol medicine; Humira for the treatment of Crohn's disease and arthritis; Imbruvica & Venclexta leukemia medicine,...

• Headquarter: Lake Bluff, Illinois, United States
• Founded: 2013
• Revenue: $45.8 billion (2020)
• Website: http://abbvie.com/

Bristol Myers Squibb is a global biopharmaceutical company specializing in medical advances in four key areas: oncology, hematology, immunology, and cardiovascular disease.

BMS is one of the world's leading pharmaceutical firms and is routinely placed on the Fortune 500 list of the top enterprises in the United States. Its overall revenue was $39.3 billion as of September 2020.

In 2019, BMS acquired Celgene (a pharmaceutical company that makes cancer and immunology drugs) to create a leading biopharmaceutical company, revenue increased 15% year over a year.

• Headquarter: 430 East 29th StreetNew York City, New York, United States
• Founded: 1887 by William McLaren Bristol, John Ripley Myers, E. R. Squibb
• Revenue: $42.52 billion (2020)
• Website: https://www.bms.com/

Sanofi S.A. is a global pharmaceutical firm based in Paris, France. In terms of prescription sales, it is the world's fifth-largest as of 2013.

Sanofi is primarily involved in the research and development, production, and marketing of pharmaceutical products for the prescription market, although the company also creates over-the-counter medications. The company's therapeutic areas include the cardiovascular, central nervous system, diabetes, internal medicine, cancer, thrombosis, and vaccines.

Featured products: Lantus anti-hyperglycemic drug; Plavix & Lovenox blood thinners; Calcium Corbiere calcium and vitamin D supplements; Taxotere is a chemotherapy drug used to treat certain types of cancer; Esperal alcohol cessation drug,...

• Headquarter: 54 Rue La BoétieParis, France 75008
• Founded: 1973
• Revenue: $42.05 billion (2020)
• Website: http://www.sanofi.com/

Pfizer Inc. is a multinational pharmaceutical and biotechnology corporation in New York. Pfizer is a pharmaceutical company that discovers and manufactures medications and vaccines for immunology, cancer, cardiology, endocrinology, and neurology.

In 2020, 50% of the company's revenues came from the United States, 8% came from each of China and Japan, and 36% came from other countries.

Pfizer and BioNTech announced a collaboration in March 2020 to investigate and develop COVID-19 mRNA vaccine candidates. Pfizer will begin testing four different COVID-19 vaccine variants in May 2020. Pfizer and BioNTech have manufactured at least 430 million vaccine doses as of early May 2021, which had been distributed to 91 different nations and territories.

• Headquarter: 235 East 42nd Street, Manhattan, New York City, U.S
• Founded: 1849 by Charles Pfizer and Charles F. Erhart
• Revenue: $41.908 billion (2020)
• Website: https://www.pfizer.com/