Before taking this medicine

If you are allergic to sertraline or are on pimozide, you should not use Zoloft. If you are on disulfiram, do not use Zoloft oral solution. Do not use Zoloft for 14 days before or after taking an MAO inhibitor. A harmful medication interaction is possible. Isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and other MAO inhibitors are available.


Inform your doctor if you are also using stimulant medication, opioid medication, herbal items, or medication for depression, mental illness, Parkinson's disease, migraine headaches, severe infections, or nausea and vomiting prevention. Sertraline interactions may result in a dangerous disease known as serotonin syndrome.


To ensure if Zoloft is suitable for you, inform your doctor if you have ever had:

    • bipolar disorder (manic depression)
    • heart disease, high blood pressure, or a stroke
    • liver or kidney disease
    • seizures
    • sexual problems
    • glaucoma
    • bleeding problems, or if you take warfarin (Coumadin, Jantoven)
    • long QT syndrome
    • low levels of sodium in your blood
    • an allergy or sensitivity to aspirin or tartrazine (food dye)
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