Brainiac
Brainiac (Vril Dox) is a fictional supervillain who appears in American comic books published by DC Comics. The character was created by Otto Binder and Al Plastino and first appeared in Action Comics issue 242 in July 1958. He is usually depicted as an extraterrestrial android or cyborg who is one of Superman's most vehement foes and a frequent Justice League foe. Brainiac is infamous for diminishing and taking Kandor, Superman's home planet Krypton's capital city, and in some continuity is even responsible for Krypton's extinction.
The name of the character is a combination of the words "brain" and "maniac". IGN listed Brainiac as the 17th Greatest Comic Book Villain of All Time in 2009. He has been voiced by Corey Burton in numerous DC animated universe television episodes, by John Noble in the animated feature Superman: Unbound, and by Jeffrey Combs in the video game Injustice 2. Brainiac has been played by James Marsters on Smallville and Blake Ritson on Krypton in live-action television.