Clean indoor equipment occasionally
Dust and other debris will accumulate more slowly indoors, but it will still have an impact on the overall efficiency and sanitation of your HVAC system. Check for dust buildup on your HVAC system's components and clean them on a regular basis.
An additional step is required for air conditioning units. You should clean your air conditioner's condensate drain with bleach once a year or so to remove any impurities that may otherwise build up and clog it, causing water to build up inside your cooling system.
To clean a condensate drain, turn off your air conditioner and disconnect the drain line. Pour a cup of bleach down the drain to remove any organic buildup. To safely disconnect the drain line, consult the owner's manual for your system.