Depression

Celiac disease causes psychological symptoms such as depression in addition to physical ones. A prior meta-analysis of 29 studies found that depression was more prevalent and severe in celiac disease adults than in the general population. Another 37-study evaluation found a relationship between celiac disease and an increased risk of depression, anxiety, and eating disorders.

Furthermore, according to one analysis, anxiety, despair, and exhaustion were often observed among patients with untreated celiac disease, which may have a severe impact on quality of life and dietary adherence. However, there are many other potential causes of depression, including:

• shifts in hormone levels
• stress
• grief
• genetics