Dosing information
Usual Adult Dose for Anxiety:
Immediate-release tablets/orally disintegrating tablets (ODT): 0.25 to 0.5 mg orally administered 3 times a day
- Maximum dose: 4 mg/day
Usual Adult Dose for Panic Disorder:
Immediate-release tablets/ODTs: 0.5 mg orally administered 3 times a day
- Maximum dose: 10 mg/day
Extended-release tablets:
- Initial dose: 0.5 to 1 mg orally once a day
- Maintenance dose: 3 to 6 mg orally per day, preferably in the morning
- Maximum dose: 10 mg/day
Comments:
- The lowest effective dose should be used, and the need for continued treatment should be evaluated on a regular basis.
- When discontinuing therapy or reducing the daily dosage, the dosage should be reduced gradually.
- A daily dosage reduction of no more than 0.5 mg every 3 days is permitted; however, some patients may require a slower dosage reduction.
- The dose of extended-release tablets may be increased in increments of no more than 1 mg per day every 3 to 4 days.
- The administration times should be spread out as evenly as possible throughout the waking hours.
Usual Geriatric Dose for Anxiety:
Elderly or debilitated patients:
Immediate-release tablets/ODTs: 0.25 mg orally administered 2 or 3 times a day.
Usual Geriatric Dose for Panic Disorder:
Elderly or debilitated patients:
Immediate-release tablets/ODTs:
- Initial dose: 0.25 mg orally administered 2 or 3 times a day
Extended-release tablets:
- Initial dose: 0.5 mg orally once a day
Comments:
- If side effects occur, the dose may be reduced.
- The lowest effective dose should be used, and the need for continued treatment should be reassessed on a regular basis.
- When discontinuing therapy or reducing the daily dosage, dosage should be reduced gradually.
