Drawbacks

You are more likely to have the following side effects if you are between the ages of 18 and 60, do not take any other medications, or have any other medical conditions:

• Adverse effects affecting the stomach, including indigestion, belching, heartburn, and bleeding. More susceptible groups include those who are older, take various stomach-affecting medications, or consume more than three glasses of alcohol every day. Compared to ibuprofen, diclofenac is more likely to have adverse effects that affect the stomach.
• Nausea, headaches, constipation, and water retention.
• There have been reports of additional adverse effects, such as tinnitus (ear ringing).
• The majority of NSAIDs have been linked to an elevated risk of catastrophic cardiovascular events like heart attack or stroke. Patients taking higher doses and those who already have cardiovascular disease may be at greater risk. In comparison to other NSAIDs like ibuprofen, diclofenac may carry a higher risk.
• May prolong bleeding, particularly if taken with other medications that also postpone blood clotting.
• Some patients, such as those with kidney illness, a history of stomach ulcers or other gastrointestinal diseases, or those who already have cardiovascular disease, may not be a good fit. During or after coronary artery bypass graft surgery, should not be administered.
• May have interactions with some other medications, including diuretics, SSRIs, ACE inhibitors, and warfarin.
• Due to the risk of fetal ductus arteriosus premature closure, NSAIDs like diclofenac should not be used in the final three months of pregnancy. Additionally, NSAID usage after 20 weeks of pregnancy may result in oligohydramnios (low amniotic fluid volume) and, in rare cases, renal damage in the developing fetus. Between 20 and 30 weeks of pregnancy, if NSAID medication is deemed required, utilize the lowest effective dose for the shortest amount of time. Do not take NSAIDs after 30 weeks of pregnancy.