Eradicate Malaria
Malaria is one of the world's deadliest ongoing insect-borne diseases, killing hundreds of thousands of people each year, primarily in Africa's high-risk tropical and subtropical regions. CRISPR is one of several lasting answers to the problem since it can be used to create something called a gene drive, which can then edit the whole mosquito gene pool to eliminate the disease entirely.
Obviously, it's not as simple as it sounds, though first results have been promising. In a recent study, researchers from multiple universities in the United Kingdom and Italy performed a similar experiment on a population of Anopheles gambiae, the mosquito species responsible for the greatest number of illnesses in Sub-Saharan Africa. The CRISPR change resulted in the eradication of the target group within a year, demonstrating that it was possible. While it's still a long way from eradicating the disease entirely, as doing so would necessitate reproducing the experiment on a much bigger scale, it's a step in the right direction.
Website: https://www.who.int/news/item/23-08-2019-malaria-eradication