He was awarded honorary Spanish citizenship

And it was done by a king, no less. In 1505, King Ferdinand bestowed upon Vespucci the title of Pilot Major of Spain, as well as a large pay. Vespucci became a naturalized Spanish citizen as a result, and he and his wife, Maria Cerezo, settled in Seville, Spain.

Amerigo Vespucci was in charge of establishing a navigation school with the purpose of modernizing navigating procedures and training pupils in standardized, consistent practice. He worked for the navigation school until his death from malaria in 1512.