Interactions

When taken with furosemide, drugs that interact with it either lessen its effect, shorten its duration of action, exacerbate side effects, or have no effect at all. Even though it is not always necessary to stop taking one of the drugs, sometimes there is an interaction between two drugs. Consult your doctor to learn how to handle drug interactions.

Typical drugs with which furosemide may interact are:

• aspirin
• allopurinol
• antibiotics, such as cephalexin, gentamicin, neomycin, or tobramycin
• anticonvulsants, such as phenytoin or fosphenytoin
• cisplatin
• cyclosporine
• duloxetine
• lithium
• methotrexate
• methylphenidate
• NSAIDs, such as diclofenac, ibuprofen, or indomethacin
• sucralfate
• other medications that lower potassium.

Diabetic patients who take oral medications may need to discuss changing the dose of their medication with their doctor.

Note that only commonly used drugs that may interact with furosemide are included in this list, which is not exhaustive. For a comprehensive list of interactions, consult the furosemide prescribing information.