Interactions

Drug interactions might change the way your treatments work or expose you to the potential for dangerous side effects. Maintain a list of all the products you use (including prescription and nonprescription medicines, as well as herbal remedies) and discuss it with your doctor and pharmacist. Do not start, stop, or adjust the dosage of any medications without first consulting your doctor. Metoclopramide is a medicine that may interact with this one.

Vraylar may interact with the following medications:

• anti-anxiety medications such as diazepam and oxazepam
• anticonvulsants, such as phenytoin
• antidepressants, such as amitriptyline, imipramine, nortriptyline
• antifungals, such as itraconazole or ketoconazole
• antihistamines that cause sedation, such as diphenhydramine, baclofen, bosentan, bupropion, cannabis
• diuretics such as bendroflumethiazide, duloxetine
• heart medications such as atenolol, timolol, or nifedipine
• HIV medications such as indinavir and ritonavir
• monoamine oxidase inhibitors, such as isocarboxazid, or phenelzine
• opioid analgesics such as codeine, oxycodone, and morphine, modafinil
• muscle relaxants such as cyclobenzaprine, rifampin
• serotonin modulators, such as nefazodone and trazodone
• sleeping pills, such as zolpidem
• some chemotherapy treatments
• some heart medications, such as diltiazem, or verapamil
• other medications used to treat mental illness, such as clozapine and thioridazine
• any medication that inhibits (itraconazole, ketoconazole) or induces (rifampin, carbamazepine) CYP3A4.