Marfan Syndrome

Even if you haven't heard of Javier Botet, there's a high chance you've seen him on film. Botet is a Spanish actor who has appeared in films such as Mama, IT, Insidious, The Conjuring 2, Crimson Peak, and the REC series. Those are all well-known horror names from the last 15 years. The reason you may not know Botet is that he plays a monster in each one of those flicks, something he has taken to as a result of Marfan Syndrome.

Botet's disease is distinguished by unusually lengthy limbs. His fingers are also unusually long and slender. It may appear weird to the average person, but in a horror film, it lends itself perfectly to an extraterrestrial image, which Botet had embraced. Marfan syndrome is caused by a mutation in the gene that codes for the protein fibrillin-1. This increases the production of a specific growth protein. As a result, connective tissue anomalies cause such long limbs and digits. Botet's body contortions on television are not special effects; they are simply the way he moves.