Muscle or joint pain

One of the major challenges to the economy of an endemic country, malaria continues to be one of the most important infectious illnesses in the world. It is a serious public health issue linked to poverty. The symptoms of malaria can be mistaken for the flu, including fever, myalgia, arthralgia, and symptoms including exhaustion, lack of well-being, abdominal pain, and headache. Malaria has a number of side effects, but it seems to particularly affect the skeletal muscular system, resulting in symptoms including muscle or joint pains. The parasite blockage of coronary arteries is another effect of malaria.

Some potential biomarkers of the level of skeletal and cardiac muscle injury include sequestration of red blood cells, elevated serum creatine kinase levels, and decreased muscle content of vital contractile proteins. These biomarkers may be helpful in predicting the success of therapies intended to shield cardiac and skeletal muscles from malaria-caused damage as well as in the prevention of sequelae.