What is Vivitrol?

Vivitrol is a brand-name intramuscular injection of naltrexone, a medication that binds to endorphin and opioid receptors in the brain and blocks the effects of alcohol and other substances. Naltrexone can be given as a pill or as an injection known as Vivitrol. A healthcare expert administers injections usually once a month. A professional would inject your Vivitrol dose for an extended release over roughly 30 days.


"Naltrexone blocks the euphoric and sedative effects of opioids such as heroin, morphine, and codeine," according to the Substance Abuse and Mental Health Administration (SAMHSA), and "binds to the endorphin receptors in the body, blocking the effects and feelings of alcohol."


Naltrexone prevents the high or positive feelings associated with alcohol and substance usage by binding to both of these receptors. Following detox from physical dependence, naltrexone in the form of Vivitrol can be used to treat opioid and alcohol use disorders. The US Food and Drug Administration first approved Vivitrol in 2006.

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