What Other Medications May Interact With Buspirone?
Top 11 in Top 12 Things to Know About Buspirone
Do not take buspirone if you have recently taken a monoamine oxidase inhibitor (MAOI) such as phenelzine (Nardil®), isocarboxazid (Marplan®), selegiline (Eldepryl®, EMSAM®), or tranylcypromine (Parnate®). The combination of buspirone and these agents can result in a significant increase in blood pressure.
The following medications may increase buspirone levels and effects:
- Diltiazem (Cardizem®, Dilacor®, Tiazac®)
- Verapamil (Calan®, Covera-HS®, Isoptin®, Verelan®)
- Erythromycin (E-Mycin®, E.E.S.®, Ery-Tab®, Eryc®, others)
- Consuming large amounts of grapefruit juice can increase the amount of buspirone in your blood
The following medications may decrease the levels and effects of buspirone:
- Rifampin (Rifadin®, Rimactane®, Rifampicin®, others)