You can take levothyroxine in the morning or at night
You've probably heard that taking levothyroxine 30 to 60 minutes before breakfast is a good idea. This is because it is more easily absorbed into the body on an empty stomach.
However, this can be difficult if your morning schedule is unpredictable. Instead, you can take levothyroxine every night before bed. It should be taken at least 4 hours after your last meal or before taking any other medications or supplements. Levothyroxine taken at bedtime is as effective as taking it one hour before breakfast. So it makes no difference whether you take it in the morning or at night. Just make sure to take it at the same time every day, away from food.
Levothyroxine has been shown to be equally effective when taken at bedtime and one hour prior to breakfast. Therefore, it makes no difference whether you take it in the morning or at night. Just be sure to take it at a different time each day than you would with food and other medications.