Johnson & Johnson (J&J) is a multibillion-dollar healthcare conglomerate that designs, manufactures, and sells a wide range of healthcare products.

It also offers services in the consumer, pharmaceutical, and medical devices and diagnostics industries. Skin and hair care products, acetaminophen products, pharmaceuticals, diagnostic equipment, and surgical equipment are among the company's offerings.

It has more than 250 operating companies in more than 60 countries. The company has over 125 manufacturing facilities in Asia, North America, Europe, and the Middle East, as well as numerous research facilities. J&J's single-dose Covid-19 immunization was endorsed for new utilize in early 2021. The FDA affirmed J&J's single-dose Covid-19 antibody for crisis utilization in early 2021, which is anticipated to assist check the spread of Covid-19 and move forward the company's execution in 2021.

• Headquarter: New Brunswick, New Jersey, U.S.
• Founded: 1886 by Robert Wood Johnson, Jame Wood Johnson, Edward Mead Johnson
• Market cap: $427.82 Billion (11/2021)
• Website: https://www.jnj.com/

Merck & Co., Inc. (NYSE: MRK) is a New Jersey-based pharmaceutical company.

Merck is best known for its mumps vaccine, primary rubella vaccine, and main trivalent measles, mumps, and rubella vaccine (MMR vaccine). Human health pharmaceuticals and vaccines are included in the company's Pharmaceutical segment.

The company is well-known all over the world. The company's major operations outside of the United States are in Europe, Japan, Asia-Pacific, and Latin America.

• Headquarter: Kenilworth, New Jersey, United States
• Founded: 1891 by Theodore Weicker, George Merck
• Market cap: $208.94 Billion
• Website: http://merck.com/

Pfizer Inc. (Pfizer) is a leading research-based worldwide biopharmaceutical company that was established in 1849 and is headquartered in New York, United States.

Medicines and vaccines, as well as consumer healthcare products, are part of Pfizer's global portfolio. Pfizer has two business segments: Pfizer Innovative Health (IH) and Pfizer Essential Health (EH) (EH).

Pfizer was the first company to develop a vaccine against Covid-19 in collaboration with BioNTech. Millions of people have received the vaccine, boosting the company's position significantly this year.

• Headquarter: 235 East 42nd Street, Manhattan, New York City, U.S
• Founded: 1849 by Charles Pfizer and Charles F. Erhart
• Market cap: $265.19 Billion
• Website: https://www.pfizer.com/

AstraZeneca PLC is a British-Swedish multinational pharmaceutical and biotechnology company headquartered in Cambridge, United Kingdom.

Its product portfolio includes treatments for cancer, cardiovascular disease, gastrointestinal disease, infection, neuroscience, respiratory disease, and inflammation, among other diseases. The Oxford-AstraZeneca COVID-19 vaccine is the company's most well-known product. The company has a $149 billion market cap.

The business is well-known all over the world. However, the United States and emerging markets generate the majority of the company's revenue, with Europe and the rest of the world following closely behind. More than 100 countries are served by the firm. The company operates in the majority of countries.

• Headquarters: 1 Francis Crick Avenue, Cambridge, UK
• Founded: 1999
• Market cap: $195.17 Billion
• Website: www.astrazeneca.com

CSL began as the Commonwealth Serum Laboratories, an Australian government agency dedicated to vaccine development, in 1916. It has operations in Australia, Germany, Switzerland, the United Kingdom, and the United States.

Biotherapies are developed and delivered by CSL. The company's main activities include biopharmaceutical and allied product research and development, manufacturing, marketing, and distribution. The company's headquarters are in Parkville, Victoria, with CSL Behring in King of Prussia, the USA, and Seqirus in Maidenhead.

CSL competes on the global stage as one of the largest and leading providers of in-licensed vaccines with its protein-based biotechnology businesses.

• Headquarters: Parkville, Melbourne, Victoria, Australia
• Founded: 1916
• Market cap: 139,81 Billion (11/2021)
• Website: www.csl.com

Sanofi, founded in 1994 and headquartered in Paris, France, is a major player in the pharmaceuticals industry. Therapeutic solutions are developed, manufactured, and marketed by the company.

Sanofi Pasteur operates in three segments: pharmaceuticals, consumer health, and vaccines. Pediatric vaccines, influenza vaccines, adult and adolescent booster vaccines, meningitis vaccines, and travel and endemic vaccines are among the products sold by the company.

Sanofi is a global healthcare company with operations in 170 countries. More than 500 million people worldwide receive company vaccines each year, and the unit distributes more than 1 billion vaccine doses.

• Headquarter: 54 Rue La Boétie, Paris, France 75008
• Founded: 1973
• Market cap: $113,43 Bilion
• Website: http://www.sanofi.com/

GlaxoSmithKline plc (GSK) is a multinational pharmaceutical corporation based in London, England.

GSK is a pharmaceutical and consumer health company that develops, manufactures, and markets products. Pharmaceuticals, Vaccines, and Consumer Healthcare are GSK's three industry segments.

The UK government decided to pay 60 million doses of a COVID-19 vaccine developed by GSK and Sanofi in July 2020. It combines Sanofi's recombinant protein-based technology with GSK's pandemic technology. The company operates in nearly 120 countries and sells its products in more than 150.

• Headquarter: 980 Great West Road, London, UK
• Founded: 2000
• Market cap: $107.50 Billion
• Website: https://www.gsk.com/

Takeda is the largest pharmaceutical company in Japan and Asia, with headquarters in Tokyo.

Metabolic disorders, gastroenterology, neurology, inflammation, and oncology are all areas where the company focuses.

The Ethical Pharmaceutical segment generates the most revenue for the company (approximately 85 percent). Consumer healthcare, reagents, clinical diagnostics, and chemical products are among the other segments.

• Headquarters: Nihonbashi, Chuo, Tokyo, Japan
• Founded: Tokyo, Japan (2005) (by merger)
• Market cap: $45.48 Billion
• Website: takeda.com

Daiichi Sankyo, the largest pharmaceutical company in Japan, specializes in the production of prescription drugs. The company was founded in 2005 when Daiichi Pharmaceutical and Sankyo merged. Daiichi Sankyo merged to become Japan's largest pharmaceutical company.

Cardiovascular, bone and joint, autoimmune, metabolic, and infectious diseases are all areas where the company has a presence. Innovative pharmaceuticals, generics, vaccines, and over-the-counter (OTC) medicines are the company's four business units.

The company sells its entire portfolio in 44 different countries.

• Headquarters: Daiichi Sankyo Building A/B 3-5-1, Nihonbashi-honcho, Chūō-Ku, Tokyo 103-8426, Japan
• Founded: Tokyo, Japan (2005) (by merger)
• Revenue: $42.70 Billion (11/2021)
• Website: http://www.daiichisankyo.com

Emergent BioSolutions Inc., based in Gaithersburg, Maryland, is a multinational specialty biopharmaceutical company.

It focuses on providing specialty products that protect and enhance life. The company develops vaccines and antibody therapeutics and operates in four business segments. Infectious diseases, oncology, and autoimmune disorders are the main focus of these products.

The company is divided into two divisions: the Biodefense division, which deals with medical countermeasures, and the Biosciences division, which deals with infectious and autoimmune diseases.

• Headquarters: Gaithersburg, Maryland, U.S.
• Founded: 1998
• Market cap: $1.88 Billion (11/2121)
• Website: https://www.emergentbiosolutions.com/