Chelsea Handler

Handler is now definitely one of the most well-known comedians in the world. She began her career in the early 2000s as a cast member of Oxygen's hidden-camera prank program Girls Behaving Badly. Handler later joined The Tonight Show as a reporter.

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However, Handler only gained popularity in 2006 when she earned her own program on E! titled The Chelsea Handler Show. Though it was brief, Handler returned to the late-night spot a year later with another program: Chelsea Lately. This program lasted seven seasons, until Handler's contract with E! terminated in 2014. Chelsea Does was the name of another Netflix documentary series in 2016. Later in her career, she presented a late-night series called Chelsea On the Streaming Network, albeit it was terminated after two seasons.

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Chelsea Handler is such a household figure in comedy that it's nearly impossible to fathom a world without her. That, it turns out, might have occurred if it had not been for a 21-year-old DUI conviction. She presented a humorous anecdote during a story-sharing session and got several praises, which motivated her to pursue a career as a comedian.

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Years active: 2001 - present

Notable show: The Chelsea Handler Show