Downsides

You are more likely to experience the following side effects if you are between the ages of 18 and 60, do not take any other medications, or have any other medical conditions:

• A headache, fatigue, flu-like symptoms, nausea, diarrhea, weight loss, abnormal bleeding, increased sweating, or a decrease in libido. Anxiety, low sodium levels, and allergic reactions (including rash) are all possibilities. It may also have an effect on heart rhythm and cause angle-closure glaucoma.
• Prozac, like other antidepressants, may raise the risk of suicidal thoughts or behavior, particularly in children and young adults.
• Can impair judgment and make it difficult to drive or operate machinery.
• Serotonin syndrome may result from a drug interaction or overdosage (symptoms include mental status changes [such as agitation, hallucinations, coma, delirium], fast heart rate, dizziness, flushing, muscle tremor or rigidity, and stomach symptoms [such as nausea, vomiting, diarrhea]). Another serious syndrome, known as Neuroleptic Malignant Syndrome, has been reported, with symptoms including high body temperature, muscle rigidity, and mental disturbances. If this syndrome occurs, stop taking Prozac immediately and seek immediate medical attention.
• May increase the risk of bleeding, especially when combined with other drugs that increase the risk of bleeding.
• May result in a decrease in total body sodium (hyponatremia); elderly people, those taking diuretics, or those who are already dehydrated are more vulnerable.
• If abruptly stopped, it may cause discontinuation syndrome. Irritability, low mood, dizziness, electric shock sensations, headache, or confusion are some of the symptoms. On withdrawal, the dosage of fluoxetine should be gradually reduced.
• Seizures are extremely rare.
• Mania may be precipitated in people with undiagnosed bipolar disorder.
• Other antidepressants, tramadol, bupropion, diuretics, St John's Wort, and drugs that prolong the QT interval may interact with this medication (such as pimozide or thioridazine).
• Some people, such as those with glaucoma, bleeding disorders, a history of seizures, liver or kidney disease, the elderly, or certain heart conditions, may be ineligible. Diabetics may require their medication dosage to be adjusted.

In general, people who are older or younger, have certain medical conditions (like liver or kidney issues, heart disease, diabetes, or seizure disorders), take other medications, or are seniors or young children are more likely to experience a wider range of side effects.