Drawbacks

• The most frequent adverse effects of amoxicillin use are skin rashes, taste changes, abdominal pain, headaches, and nausea (fewer than 10% of patients experience these).
• Those who are allergic to penicillin risk experiencing an allergic response. Anaphylaxis occurs in extremely few people (less than 0.01% of the time).
• Not effective against bacterial strains that produce beta-lactamases.
• Amoxicillin resistance should be assumed for Staphylococci bacteria that are resistant to methicillin/oxacillin.
• Almost all antibacterial drugs, including amoxicillin, have the potential to cause severe diarrhea linked to Clostridium difficile.
• Amoxicillin should be avoided in patients with mononucleosis because of the significant risk of rash associated with ampicillin-like antibiotics like this one.
• May result in false-positive glucose findings from various urine tests.
• In those who have a history of penicillin allergies, avoid.

Amoxicillin allergies can manifest suddenly and severely, so it's important to seek emergency medical care as soon as you can. Such a reaction frequently begins with a mental shift, a skin rash with severe itching (typically starting in the fingertips and spreading quickly to the groin area), and feelings of fever, nausea, and vomiting. It is imperative to treat very carefully any additional symptoms that even slightly raise suspicion. A rash, for example, is a milder allergy symptom that might appear at any point during therapy or even up to a week after it has ended. Amoxicillin allergies in certain persons can have fatal side effects like anaphylaxis.