Interactions

When taken with amoxicillin, medications that interact with it may either lessen its impact, shorten its duration of action, amplify its negative effects, or have no impact at all. Even while it is not always necessary to cease taking one of the drugs, sometimes there is an interaction between two drugs. Consult your doctor to learn how to handle drug interactions.

Typical drugs with which amoxicillin may interact are:

• allopurinol (may increase the risk of rash)
• blood thinners known as anticoagulants, like warfarin (may prolong bleeding time)
• oral conceiving pills (may decrease absorption leading to reduced efficacy)
• other antibiotics like tetracycline, macrolides, sulfonamides, and chloramphenicol
• probenecid (may raise blood concentrations of amoxicillin)

With copper reduction tests (such as Benedict's or Fehling's solution), amoxicillin may produce a false-positive result for glucose in the urine, but not with enzyme-based assays.