Greetings
Mexicans are very ceremonial and polite. When meeting or being introduced, businesspeople and strangers shake hands, whereas friends (women to women or men to men) may deliver a "air kiss" or a kiss on the cheek. Male acquaintances or buddies may offer each other three pats on the back and a firm hug. When in doubt, extend your hand.
When addressing seniors, subordinates, superiors, and strangers, it is customary to use the formal form of you (usted) rather than the informal tu. But because so few Americans speak Spanish, any polite attempt is acceptable (although using the correct pronoun is, naturally, best). Say "adios" (goodbye) or "hasta luego" while departing (see you later).
A courteous way to say "Excuse me" before asking someone for information or directions is to say "Desculpe" before asking them a question. Similar to this, it's more courteous to ask "Habla inglés" rather than presuming everyone you meet in Mexico speaks English.