He died in 1892 as a result of brain cancer

Another fact about Louis Vuitton is that he died in 1892 as a result of brain cancer. Demand plummeted precipitously in 1871 as a result of the Franco-Prussian War, and Vuitton's workshop was in disarray. The Franco-Prussian War, often known as the War of 1870 in France, was a struggle between the Second French Empire and the North German Confederation commanded by the Kingdom of Prussia. Many of his tools had been stolen, and his staff had gone. Vuitton quickly rebuilt, opening a new store at 1 Rue Scribe, near a prominent jockey club in the heart of Paris. Vuitton debuted a new line in 1872, featuring beige monogrammed designs with a red stripe that would become a characteristic of his business. He died in 1892 as a result of severe and aggressive brain cancer (glioblastoma).

Vuitton continued to operate out of 1 Rue Scribe for the following 20 years, innovating high-quality, luxury luggage, until his death on February 27, 1892, at the age of 70. But the Louis Vuitton brand did not die with its namesake. The Louis Vuitton brand would grow into the world-renowned luxury leather and lifestyle brand it is today under his son Georges, who devised the company's famed LV monogram and future generations of Vuittons.