Interactions
When taken with amlodipine, medications that interact with the drug may lessen its effects, shorten their duration, cause more side effects, or have no effect at all. Even while it is not always necessary to cease taking one of the drugs, sometimes there is an interaction between two drugs. Consult your doctor to learn how to handle drug interactions.
Typical drugs with which amlodipine may interact are:
- anticonvulsants, such as carbamazepine or fosphenytoin
- antifungal agents, such as itraconazole or ketoconazole
- alfentanil
- amiodarone
- beta-blockers, such as atenolol, labetalol, or metoprolol
- buspirone
- benzodiazepines such as midazolam or triazolam
- carbamazepine
- cimetidine
- cyclosporine
- rifampin
- lovastatin or simvastatin
- quinidine
- NSAIDs, such as diclofenac, ibuprofen, and indomethacin, may decrease the blood pressure-lowering capabilities of amlodipine
- sildenafil
- other medications that inhibit or induce CYP 3A4.
