Interactions
When used with Doxycycline, certain medications may either lessen the drug's impact, shorten its duration of action, exacerbate adverse effects, or have no effect at all. Even while it is not always necessary to cease taking one of the drugs, sometimes there is an interaction between two drugs. Consult your doctor to learn how to handle drug interactions. Tetracyclines are generally less absorbed when taken with food, especially calcium-containing meals; however, doxycycline does not seem to be as absorbed by food or milk to the same level as other tetracyclines.
Typical drugs with which Doxycycline may interact are:
- Antacids that may interfere with doxycycline absorption include those made of aluminum hydroxide, calcium carbonate, magnesium hydroxide, or sodium bicarbonate.
- anticonvulsants, such as phenytoin, phenobarbital, or primidone
- bismuth subsalicylate
- calcium supplements
- iron supplements
- multivitamins
- oral contraceptives (doxycycline may reduce the effectiveness of estrogen-containing oral contraceptives)
- penicillin
- warfarin.
