Interactions
Medicines that interact with famotidine may reduce its effect, shorten its duration of action, increase side effects, or have no effect when combined. An interaction between two medications does not always necessitate the discontinuation of one of them; however, it can. Consult your doctor about how to handle drug interactions.
Famotidine may interact with the following medications:
- anticoagulants (blood thinners), such as warfarin, or other drugs that have blood-thinning effects such as aspirin or NSAIDs
- antifungals, such as fluconazole, itraconazole, ketoconazole, or voriconazole
- cancer treatments, such as bosutinib, dabrafenib, dasatinib, erlotinib, neratinib, or pazopanib
- epilepsy medications, such as carbamazepine, fosphenytoin, phenobarbital, or phenytoin
- fentanyl
- hepatitis medications, such as boceprevir, ledipasvir, sofosbuvir, and telaprevir
- HIV medications (eg, atazanavir, indinavir, ritonavir, or saquinavir)
- iron supplements, such as ferrous fumarate, ferrous gluconate, or ferrous sulfate
- loperamide
- metformin
- multivitamins
- theophylline
- warfarin.
It should be noted that this list is not exhaustive and only includes common medications that may interact with famotidine. For a complete list of interactions with famotidine, consult the prescribing information.