Response and effectiveness
Within an hour of taking it, it begins to suppress gastric acid. The maximum effect is dose-dependent and occurs within one to three hours. Famotidine has an effect that lasts 10 to 12 hours after a single dose.
Peak effects are felt one to three hours after taking a dose. Symptomatic relief for GERD occurs within 24 hours of beginning famotidine therapy.
For 10 to 12 hours, one dose of famotidine significantly inhibits gastric acid secretion.
Food does not appear to affect famotidine absorption or peak concentrations.