Leptin
Leptin is a fullness hormone that informs your hypothalamus — the part of your brain that regulates your appetite — that you're full.
Obese people, on the other hand, may have leptin resistance. This implies that the signal to stop eating does not reach your brain, leading to overeating. As a result, your body may create even more leptin until your levels reach dangerously high levels. The exact cause of leptin resistance is unknown, however, it might be caused by inflammation, gene mutations, or excessive leptin production, which can occur with obesity. Because obesity is linked to leptin resistance, it's critical to keep a healthy weight. Furthermore, evidence shows that a reduction in body fat may help in the reduction of leptin levels.