Muscle weakness

Generalized muscle weakness is not unusual; in fact, it is fairly prevalent and determining the cause, whether due to a vitamin B1 shortage or another medical condition, can be challenging. In summary, most people experience transitory muscle weakness at some point in their lives. However, persistent muscle weakness with no apparent cause or reason may indicate thiamine deficiency. Patients with thiamine deficiency frequently experience muscular weakness.

These impairments occur in the sock-glove distribution and are bilateral and relatively symmetric. The impact the majority of the lower extremities, beginning with paresthesias in the toes, heat in the feet (particularly at night), calves muscle cramps, shin pain, and paresthesias. Early symptoms include weak leg muscles, difficulty rising from a crouching position, and diminished feeling in your toes. A persistent deficiency will worsen polyneuropathy, which might impair the arms.