Nerve damage
Damage to the nerves, often known as neuropathy, is one of the most well-known side consequences of persistent, severe thiamine deficiency (beriberi). Beriberi, also known as thiamine deficiency, is a disease caused by a vitamin B1 deficiency. It is more common in underdeveloped countries among persons who eat a diet high in white rice or processed carbs. Thiamine insufficiency neuropathy was one of the earliest deficient syndromes to be discovered in humans.
Wet beriberi and dry beriberi are the two forms of beriberi that can develop. Wet beriberi is associated with heart failure, whereas dry beriberi is not. Wet beriberi is a medical emergency that can kill you in a matter of days if not handled. Dry beriberi causes nerve injury, which can lead to muscular weakness and finally paralysis. Beriberi is a life-threatening condition if left untreated.