Side effects of fentanyl

Adverse effects, especially the respiratory depressant effects of fentanyl, are more common in older people than in younger people. Healthcare professionals must monitor people in this age group frequently and with extreme caution.


Side effects of fentanyl include:

  • drowsiness
  • confusion
  • constipation
  • weakness
  • dry mouth
  • constricted pupils
  • unconsciousness
  • slowed respirations
  • decreased heart rate
  • nausea
  • sweating
  • flushing
  • stiff or rigid muscles
  • tight feeling in the throat
  • difficulty concentrating

Adverse effects associated with transdermal fentanyl patches include:

  • discoloration
  • rash
  • itching
  • swelling at the site of application
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