Tiredness and Low Energy
A lack of vitamin B6 might make you fatigued and sluggish, due to vitamin B6 aids in the production of hemoglobin - a protein found in red blood cells that aids in the transport of oxygen throughout the body. Anemia occurs when the cells do not receive enough oxygen due to a lack of hemoglobin. The body may get fatigued and weak as a result of this.
There have been occurrences of anemia linked to B6, however, treatment with pyridoxine hydrochloride (HCl) has not proven successful. Supplementing with pyridoxal 5 W-phosphate (PLP), the most active form of B6, was able to cure the anemia. B6 can be purchased as a supplement in either form, however, pyridoxine HCl is more popular and usually costs less than PLP. A B6 deficiency can contribute to fatigue in addition to anemia because it plays a role in the production of the sleep-promoting hormone melatonin.