What other drugs will affect Ambien?

Drug interactions can increase the risk of unwanted effects. Therefore, to reduce drug interactions, tell your doctor about all the medications you are taking before taking zolpidem.

Absolutely do not arbitrarily use, stop or change the dose of any medicine, including Ambien without the guidance of the doctor.

Sodium Oxybate may interact with the drug Ambien. A number of other drugs affect the elimination of zolpidem from the body and the action of this medication for insomnia. These drugs include azole antifungals (such as ketoconazole), and rifampin.

The risk of serious side effects (such as slow breathing, drowsiness, and dizziness) is increased if Ambien is taken with other medicines that also cause drowsiness or breathing disturbances.

Talk to your doctor about products you are taking such as opioid pain relievers or cough suppressants (such as codeine, hydrocodone), alcohol, marijuana, sedatives or anxiety relievers (such as alprazolam, lorazepam, zopiclone), muscle relaxants (such as carisoprodol, cyclobenzaprine), antihistamines (such as cetirizine, diphenhydramine).