Darkseid is a DC Comics supervillain that appears in American comic books. The character was created by writer-artist Jack Kirby and initially appeared in Superman's Pal Jimmy Olsen issue 134 in December 1970, before being officially debuted in the inaugural issue of The Forever People in February 1971. He is portrayed as the tyrant Lord of Apokolips, whose ultimate purpose is to control the multiverse by removing all hope and free will from sentient beings. Darkseid, a New God and one of the most powerful entities in the DC Universe, began as the main antagonist in Jack Kirby's Fourth World epic before becoming one of Superman's greatest foes and the Justice League's archenemy.

IGN named him the 6th Greatest Comic Book Villain of All Time, and Wizard magazine named him the 23rd Greatest Villain of All Time. Darkseid has been adapted from the comics into a variety of media, including Michael Ironside in the DC animation universe, Andre Braugher in Superman/Batman: Apocalypse, and Tony Todd in the DC Animated Movie Universe voicing the character. Ray Porter played the character in Zack Snyder's Justice League, which was released in 2021 as part of the DC Extended Universe.

Vandar Adg of the Blood Tribe, better known as Vandal Savage, is a supervillain that appears in DC Comics' American comic books. He first appeared in Green Lantern Vol. 1 issue 10 (1943), when he is described as a Cro-Magnon warrior who became immortal after coming into contact with a weird meteorite. He has plagued the Earth as a villain and occasional conqueror for 50 thousand years, going by various identities but most commonly calling himself Vandal Savage. Despite not possessing any superhuman abilities beyond his capacity to survive and heal from mortal wounds, he is a smart and vicious tactician with vast expertise in different sciences and techniques of fighting, able to fight effectively against many heroes.

Immortal or reincarnating heroes such as Immortal Man, Hawkman, Hawkgirl, and Resurrection Man have been his most frequent foes throughout history, and he is also a recurring foe of the Justice League. Vandal Savage was named the 36th best comic book villain of all time by IGN in 2009.

In Smallville, Vandal Savage makes his live-action debut as "Curtis Knox", played by Dean Cain. The role was eventually represented by Casper Crump on The CW's Arrowverse. He appeared as the main enemy in "Heroes Join Forces", a crossover between seasons two and four of The Flash, as well as the first season of Legends of Tomorrow.

The Crime Syndicate is a group of supervillains who are the evil counterparts of the Justice League in one of DC Comics' alternate universes. The initial group was known as the Crime Syndicate of America (CSA). In August 1964, Justice League of America, issue 29 introduced the first superpowered Crime Syndicate team. The Crime Syndicate of Amerika (with the variant spelling of America) was originally seen in the 2000 JLA: Earth 2 graphic novel.

A related successive group on Earth-3 is known as the Crime Society of America and first appeared in 52 issues 52, and was later featured in Countdown to Final Crisis. A "Golden Age" supervillain group, the Crime Society was to Earth-2 what the Anti-Matter Crime Syndicate of Amerika was to Earth-0 until it was removed from continuity following DC's 2011 Flashpoint storyline and The New 52 company-wide reboot. Following this, a singular Crime Syndicate is the Earth-3 counterpart of the Earth-0 Justice League, first appearing in Justice League issue 23 (October 2013), and the main focus of the company-wide crossover storyline Forever Evil. The events of that storyline have far-reaching consequences for the DC Universe and for the Crime Syndicate characters who survived and that remained on Earth-0 in one form or another after its events.

Amazo is a fictional character who appears in DC Comics' American comic books. Gardner Fox and Mike Sekowsky invented the character, who originally appeared as a foe of the Justice League of America in The Brave and the Bold issue 30 (June 1960). The character has appeared in comic books and other DC Comics-related items, such as animated television programs, trading cards, and video games, since his introduction during the Silver Age of Comic Books.

Amazo is a villainous android built by Professor Ivo and equipped with technology that allows him to imitate the talents and capabilities of the superheroes he battles (typically the Justice League) as well as construct duplicates of their weapons (though these copies are less powerful than the originals). He frequently uses the Flash, Aquaman, Martian Manhunter, Wonder Woman, and Green Lantern as his default powers (the Justice League founding members that he first fought). He resembles and is frequently likened to the Marvel android villain Super-Adaptoid, who was created later.

Amazo began as the A-Maze Operating System in the DC Comics New 52 reality before evolving into an android capable of reproducing superhuman abilities. Later, a sentient Amazo Virus infects and takes over the mind of research scientist Armen Ikarus. The Amazo Virus infects other people using Ikarus as a host, giving them superpowers and controlling their thoughts before they die within 24 hours. Multiple Amazo robots debuted in live-action media in the Arrowverse crossover event Elseworlds.

Solomon Grundy (also known as "The Reanimated Corpse of One Solomon J Grundy") is a fictional character that appears in DC Comics as a supervillain and antihero. He was once portrayed as a murder victim who was resurrected as a corporeal revenant or zombie, while later renditions of the character have occasionally depicted a different origin. His name comes from the nursery rhyme "Solomon Grundy" from the nineteenth century.

Grundy was first created as an adversary of comic book hero Alan Scott (the first Green Lantern) but has since grown to be a major foe of Superman, Batman, and other Justice League members. Later writers have given him ties to Swamp Thing, one of DC's horror-fantasy characters, as a revenant whose past frequently involves coming back to life after being dumped in the swamp.

Solomon Grundy initially appears in the DC Animated Universe, as an antihero. In the second season of the Arrowverse series Arrow, he made his live-action debut as Cyrus Gold, and in Fox's television series Gotham, he played Butch Gilzean. Solomon Grundy has featured in CGI form in the first and second seasons of the DC Universe and The CW network's television series Stargirl.

Despero is a DC Comics supervillain that appears in their comic books. He has gone through as many alterations as the League itself. The tyrant began as a feeble man with little ability other than mind control. His hatred for the Justice League, on the other hand, pushed him to his limits, and he eventually became a force to be reckoned with. When records state Despero avoided death and regenerated just to fight the League again, it isn't a figure of words. Gardner Fox and Mike Sekowsky invented the character, who originally appeared in Justice League of America issue 1 (October 1960).

The character first appeared in comic books during the Silver Age of Comic Books and has since appeared in numerous DC Comics-related goods like animated television shows and feature films, trading cards, and video games. The Martian Manhunter, Booster Gold, the Green Lantern Corps, and the Justice League are all enemies of his. Tony Curran portrayed Despero in the live-action Arrowverse television series The Flash in the five-part Armageddon event in the eighth season. Despero was ranked the 96th best comic book villain of all time by IGN in 2010.

Ra's al Ghul is a supervillain who appears in DC Comics' American comic books as a nemesis of the crime-fighting vigilante Batman. The character was first introduced in Batman issue 232's "Daughter of the Demon" by editor Julius Schwartz, writer Dennis O'Neil, and illustrator Neal Adams (June 1971). The character, modeled mainly on yellow peril "Devil Doctor" Fu Manchu, has since evolved into one of Batman's most lasting foes and is a member of Batman's rogues' gallery, yet because of his high position as a supervillain, he has also clashed with Superman, Green Arrow, and other DC Universe heroes.

Ra's al Ghul's name means "Head of the Ghoul" in Arabic, and he is best known as the commander of the League of Assassins. He is Sensei's son, the father of Talia al Ghul, Nyssa Raatko, Dusan al Ghul, and Damian Wayne's maternal grandfather. The Lazarus Pits, which bring the dead back to life, are frequently mentioned in Ra's al Ghul stories. Ra's life has been significantly extended by the Lazarus Pits, making him extremely dangerous because he has spent decades honing his combat talents.

Ra's al Ghul has appeared in a number of different media adaptations. David Warner in the DC Animated Universe, Liam Neeson in The Dark Knight Trilogy, Jason Isaacs in Batman: Under the Red Hood, Dee Bradley Baker in the Batman: Arkham video game series, Matt Nable in the Arrowverse television series, and Alexander Siddig in Gotham have all portrayed the role.

Deathstroke (Slade Joseph Wilson) is a DC Comics supervillain who appears in American comic books. Deathstroke the Terminator debuted in The New Teen Titans issue 2 in December 1980, created by Marv Wolfman and George Pérez. He is frequently represented as one of the DC Universe's deadliest and most costly assassins and is a major foe of various superhero teams, including the Teen Titans, Titans, and Justice League. Individual heroes such as Dick Grayson (as Robin and subsequently Nightwing), Batman, and Green Arrow face him as well. Jericho, two incarnations of Ravager (Grant and Rose Wilson), and Respawn are all descendants of Deathstroke.

Wizard magazine listed the character as the 24th Greatest Villain of All Time, and IGN ranked him as the 32nd Greatest Comic Book Villain of All Time. He has appeared in a number of media adaptations, including several Batman-related productions and the Teen Titans animated series, where he is voiced by Ron Perlman. Deathstroke has been played in live-action by Manu Bennett on The CW's Arrowverse television show, Esai Morales as the main antagonist in the second season of the DC Universe series Titans, and Joe Manganiello in the DC Extended Universe with a cameo in the 2017 film Justice League.

Bane is a supervillain that appears in DC Comics' American comic books. He debuted in Batman: Vengeance of Bane #1, created by writer Chuck Dixon and artist Graham Nolan (January 1993). Bane is a violent foe of the superhero Batman, and he is part of the rogue's gallery of villains that make up the Batman rogues gallery. Bane is frequently credited as the only villain to have "broken the bat", beating him both physically and mentally, because of a combination of overwhelming power and brilliant intelligence. He is the son of King Snake, another of Batman's foes.

Robert Swenson portrayed Bane in the 1997 film Batman & Robin, while Tom Hardy played him in the 2012 film The Dark Knight Rises. Bane was also played by Shane West in the final season of the FOX television series Gotham. IGN's list of the Top 100 Comic Book Villains of All Time ranked Bane as 34.

Trigon was the ruler of an unknown alien world at the time. Three powerful aliens are known as the Divine eventually arrived on his planet in an attempt to cleanse his soul of evil. To feast on his soul, the Divine summoned the huge Heart of Darkness. Trigon, on the other hand, was able to absorb the power of the Heart of Darkness, which housed the wickedness of a hundred galaxies and transform himself into a supreme power capable of destroying innumerable worlds. Before shredding their flesh and wearing their skin, he slaughtered The Divine, who he revealed to be his parents. Trigon would bring women from distant worlds to mate with and impregnate them, then send them back to spread his evil and destroy countless universes. He is an adversary of the Teen Titans and the Justice League, the father and the arch-enemy of the superhero Raven, and the husband of the human Arella.

Trigon appears in the Teen Titans animated series voiced by Keith Szarabajka (in the first season) and by Kevin Michael Richardson (in the fourth season). Trigon appears in the animated film Justice League vs. Teen Titans, voiced by Jon Bernthal. This version can create and send demons to possess others, a trait he uses to manipulate the Justice League into attacking the Teen Titans and capture his daughter Raven.