The Silver Swan is a fictional character that frequently appears in DC Comics publications and related media as a regular foe of Wonder Woman. She initially appeared in 1982 in Wonder Woman (vol. 1) issue 288, written by Roy Thomas and drawn by Gene Colan, with the superhuman power to emit a terrible sonic wail. As comic book continuities have developed and shifted since then, the character has had various updates.

Helen Alexandros, the first Silver Swan, debuted in Wonder Woman (vol. 2) issue 15 in 1988, Valerie Beaudry, the second Silver Swan, debuted in Wonder Woman (vol. 2) issue 15 in 1989, and Vanessa Kapatelis, the third and current Silver Swan, debuted in 2001 in Wonder Woman (vol. 2) issue 171. All three characters' backstories are based on Hans Christian Andersen's fairy tale The Ugly Duckling: Alexandros, Beaudry, and Kapetelis all believe they are undesirable, unattractive, or unwanted in various ways, only to be transformed into extraordinarily beautiful (and vengeful) super-powered women.

Giganta is a fictional villain who appears in DC Comics publications and related media, most notably as a regular foe of Wonder Woman and an occasional foil of the Atom. Wonder Woman (vol 1) issue 9, written by Wonder Woman creator William Moulton Marston and illustrated by Harry G. Peter, launched her as a ruthless strongwoman in 1944. She has since become one of Wonder Woman's most known and persistent antagonists, appearing in every major era of the hero's comic book adventures and being adapted for television and animation on numerous occasions.

Giganta has been adapted into a number of Wonder Woman-related television shows and animated films. In the 1979 NBC live-action Legends of the Superheroes TV programs, she was teamed with the Atom (actor Alfie Wise) for a comical tell-all interview about their claimed "strange couple" affair, and she was played by trans actor Aleshia Brevard. In a 1976 episode of the ABC TV series Wonder Woman, actor Mickey Morton wore a gorilla suit to play a version of the character (dubbed "Gargantua"). Giganta has been voiced by Kimberly Brooks, Grey DeLisle, Joan Gerber, Jennifer Hale, and Vanessa Marshall in animation.

Veronica Cale is a fictional character who frequently appears in DC Comics publications and related media as a regular foe of Wonder Woman. She was created by comic book writer Greg Rucka and originally appeared in Wonder Woman (series 2) issue 196 in 2003. She is a brilliant pharmaceutical tycoon and cruel criminal mastermind. Cale is a bright scientist as well as a brilliant businesswoman, and she makes use of her vast intellect and fortune for both good and evil. She despises Wonder Woman, believing that she does not merit society's great regard as a feminist role model. Cale dreams in vain that she, too, might be a "Wonder Woman", and this enmity stems from a deep-seated hatred of her adversary's power.

Veronica Cale has appeared heavily in the reformulated origins of several of Wonder Woman's antagonists, including the Silver Swan and Doctor Cyber, following DC Comics' 2016 continuity reboot known as Rebirth. In addition to the Cheetah, Circe, Doctor Psycho, Deimos, and Phobos, her plans against Wonder Woman have brought her into a confrontation with various other members of the hero's rogues gallery, including the Cheetah, Circe, Doctor Psycho, Deimos, and Phobos. Colonel Marina Maru, the post-Rebirth Doctor Poison, who serves as one of her top criminal agents, has a long-standing relationship with her.

Doctor Poison is a fictitious character who frequently appears in DC Comics publications and related media as a recurring foe of Wonder Woman. She initially appears in 1942's Sensation Comics (vol 1) issue 2, written by Wonder Woman creator William Moulton Marston and illustrated by Harry G. Peter, and she retains the distinction of being Wonder Woman's first costumed supervillain.

Various versions of Doctor Poison have been depicted as the narrative continuity of Wonder Woman comics has been modified by different writers and artists over the years, usually as perversely cruel toxicologists of Japanese heritage. Since her introduction, the character has gone through at least four different incarnations: (1) Doctor Poison Princess Maru of the Golden Age, (2) the Modern Age Doctor Poison, Princess Maru's mysterious unnamed granddaughter, who first appeared in 1999's Wonder Woman (vol 2) issue 151, (3) the short-lived New 52 Doctor Poison, a Russian scientist known only as Dr. Maru, who first appeared in 2016's Wonder Woman (vol 4) issue 48, and (4) Colonel Marina Maru, a Post-Rebirth reformulation of the character who leads an elite team of mercenaries known as "Poison".

Beyond comic books, Doctor Poison has appeared in various Wonder Woman media productions, including Patty Jenkins' high-profile 2017 feature film Wonder Woman (in which Elena Anaya portrays the character) and the 2019 Warner Brothers animated film Wonder Woman: Bloodlines (in which she was played by voice actor Courtenay Taylor).

Circe is a DC Comics character who appears in many publications and media. She is an evil sorceress and key recurring foe of the superhero Wonder Woman, based on the Greek mythical person of the same name who imprisoned Odysseus in Homer's Odyssey. Since her first appearance in Wonder Woman (vol 1) issue 37 in 1949, she has been portrayed in a variety of ways, but her characterization has remained consistent in key aspects: immortality, stunning physical beauty, a powerful command over sorcery, a penchant for turning humans into animals (like her mythological antecedent), and a fondness for humiliation.

Circe debuted as a Wonder Woman enemy, but she would spend the following 43 years as an antagonist for other DC Comics characters, including Rip Hunter, the Sea Devils, and, most notably, Superman and Supergirl, for whom she was a constant foil (and occasionally ally) throughout the late 1950s and 1960s. She would return to her roots as a member of Wonder Woman's rogues' gallery in 1983, at the end of the Bronze Age of Comics, and rise to become one of the hero's most significant Modern Age foes, appearing frequently in Wonder Woman stories throughout DC Comics' post-Crisis, New 52, and Rebirth continuities.

The Cheetah is a fictional character that has appeared in DC Comics publications and related media, most notably as a significant recurrent foe of Wonder Woman. She, like her opponent, was created by William Moulton Marston and first appeared in Wonder Woman (vol 1) issue 6 in the autumn of 1943. Her sleek, spotted look has earned her the title of "one of Wonder Woman's most famous opponents", and she has appeared as a persistent foe in every era of the hero's comic book adventures.

Since the character's inception, the Cheetah has had four different incarnations: Priscilla Rich (the Golden and Silver Age Cheetah), Deborah Domaine (the Bronze Age Cheetah), Dr. Barbara Ann Minerva (the Post-Crisis and current Cheetah), and Sebastian Ballesteros (the Post-Crisis and current Cheetah) (a male usurper who briefly assumed the role in 2001). The Cheetah was named the 69th best comic book villain of all time by IGN in 2009.

The Cheetah character has been adapted in a variety of media outside of comics since her inception, including animated shows, films, and video games. The character's live-action premiere was Kristen Wiig's portrayal of Dr. Barbara Ann Minerva in the DC Extended Universe film Wonder Woman 1984, which was released in 2020.

Ares (also referred to as Mars) is a fictional character that appears in DC Comics and associated media. He is the Olympian god of war and a significant recurring antagonist of the superhero Wonder Woman, based on the Greek mythological person of the same name. He has appeared as a persistent antagonist in every era of Wonder Woman's comic book adventures, as well as in many other media adaptations of her stories.

Ares first debuted in Wonder Woman (vol 1) issue 1, penned by Wonder Woman creator William Moulton Marston and published in the summer of 1942. His name is Ares in the introduction panels, but the narration goes on to say that he is "now called" by his Roman name Mars. For the next 45 years, he was known by that name (with infrequent exceptions) until George Pérez and Greg Potter, as part of their reboot of the Wonder Woman comic book mythos in 1987, reinstated the Greek name, Ares.

Varying versions of Mars/Ares (with various personalities and physical appearances) have been presented as the narrative continuity of Wonder Woman comics has been modified by different authors and illustrators over the years, however, most have been represented wearing Greek hoplite or Roman gladiator armor. George Pérez's longest-running look for the character is that of a red-eyed Greek warrior wearing black and indigo combat armor, his face veiled under an Attic helmet. After DC's continuity was rewritten in 2011 (dubbed "The New 52"), the character went through numerous different aesthetic interpretations (including one based on the physical appearance of then-Wonder Woman writer Brian Azzarello) before returning to his Pérez-inspired warrior style.

Doctor Cyber is a fictional character appearing in DC Comics publications and related media, commonly as a recurring adversary of the superhero Wonder Woman. She first appeared late in the Silver Age of Comics in 1968's Wonder Woman (vol 1) issue 179, written by Dennis O'Neil and illustrated by Mike Sekowsky and Dick Giordano.

Dr. Cyber was the intelligent head of a massive global criminal network in her Silver Age appearances. She merged characteristics of the femme fatale and dragon lady character stereotypes at first. She was beautiful, vain, and either British or Asian in heritage (or both). Dr. Cyber's subsequent Bronze Age appearances included science fiction features, such as an unnerving muzzle mask and a technologically advanced exoskeleton when her face was injured in an accident. These cybernetic upgrades boosted her physical strength and gave her the capacity to absorb and divert energy through the use of blasts fired from her hands. Despite the increased strength, Dr. Cyber's disfigurement caused her to become increasingly emotional: she grew obsessed with recapturing her beauty by transferring her mind into Wonder Woman's body, a feat she attempted multiple times with the help of her operative Doctor Moon.

Baroness Paula von Gunther is a fictional character that has appeared in DC Comics and associated media. The Baroness was created by William Moulton Marston in Sensation Comics 4 (1942) as an antagonist for his comic book heroine Wonder Woman, and she would go on to become the Amazing Amazon's first regular foe. Despite being a cold-blooded Nazi spy and saboteur in her early appearances, the Baroness would convert into Wonder Woman's ally (albeit one who periodically slipped into villainy), appearing in Wonder Woman stories throughout the Golden, Silver, and Bronze Ages of Comics.

Wonder Woman, her supporting characters, and many of her antagonists were reimagined and reintroduced after DC Comics rebooted its continuity in 1985 (in a publication event known as the Crisis on Infinite Earths). Though the Baroness was initially absent from this updated set of tales, Wonder Woman writer/artist John Byrne reintroduced her to the continuity in 1998, returning her to her beginnings as a wicked Nazi mastermind. The Baroness was reimagined by Byrne as an occult enthusiast who used her mystical knowledge to serve the Third Reich, and she became a receptacle for the wicked supernatural creature Dark Angel.

The Duke of Deception is a fictional character that frequently appears in DC Comics publications and related media as a regular foe of Wonder Woman. The Duke, a demigod of deception and manipulation, was first introduced as a deceitful operative of the battle god Mars/Ares and would go on to become one of Wonder Woman's most tenacious opponents, appearing more frequently than any other during her Golden and Silver Age adventures.

Though his roots and associations have always been interpolated into the Greek mythology that informs the Wonder Woman mythos, he would come to be portrayed as a more independent opponent (with a variety of distinct character designs). The Duke's comic book appearances have never definitively proven his true identity, the 2020 feature film Wonder Woman 1984 suggests he is Dolos, the Greek mythological deity of deception and falsehoods.