Johnson & Johnson was formed in 1886 and is a pharmaceutical, medical device, and consumer goods packaging company. The corporation is included in the Fortune 500 list of businesses. The Johnson & Johnson group is attempting to integrate the broad spectrum of science and technology to combine its own surgical, orthopedic, and interventional treatments in an increasingly drastically changing environment. It is to build and deliver patient-centered goods and services based on the great ideas of other companies.

Johnson & Johnson has been a pioneer in the medical sector, continually working to improve the level of treatment by expanding patient access, increasing results, and lowering system costs. contribute value to the healthcare system. Johnson & Johnson develops an intelligent, people-centered healthcare system to help patients recover faster, live longer, and be healthier.

Finding a mechanism to administer vaccines on a global scale is vital as a fresh wave of #COVID19 spreads over the world. Dr. Paul Stoffels, Johnson & Johnson's Vice Chairman of the Executive Committee and Chief Scientific Officer, discusses how we can work together to achieve this goal by forming cross-sector alliances, focusing on innovation, and more. The pharmaceutical and consumer goods giant is worth a market cap of $428.7 billion. They developed the third vaccine authorized for use in the U.S and were named among the Time100 Most Influential Companies List in 2021. ( refer: https://www.visualcapitalist.com/ )

Country: USA

Market Cap Value: $428.66 Billion

Website: https://www.jnj.com/

Facebook: https://www.facebook.com/jnj

F. Hoffmann-La Roche AG, commonly known as Roche, is a Swiss multinational healthcare company that operates worldwide under two divisions: diagnostics and pharmaceuticals. ( refer: https://www.chemeurope.com/ )

Roche has also developed a number of HIV tests and antiretroviral medications. In 1992, it purchased the patents for the polymerase chain reaction (PCR) method. The United States FDA approved Hoffman-LaRoche's HIV protease inhibitor saquinavir in 1995, ushering in the era of highly active anti-retroviral therapy (HAART). Within two years of its approval (and four months later of ritonavir), annual AIDS fatalities in the United States plummeted from over 50,000 to around 18,000 within two years.

The FDA approved Roche Diagnostics' high-volume Sars-CoV-2 diagnostic test in March 2020, allowing it to analyze 1,400–8,800 samples within 24 hours using the company's proprietary cobas 6800–8,800 molecular testing technology. Roche Diagnostics is a company that makes diagnostic equipment and reagents for use in research and medical diagnosis. Roche Applied Science, Roche Professional Diagnostics, Roche Diabetes Care, Roche Molecular Diagnostics, and Roche Tissue Diagnostics are the company's five major business sectors (Ventana).

Country: Switzerland

Market Cap Value: $320.41 Billion

Website: https://www.roche.com/

Instagram: https://www.instagram.com/roche/

Pfizer, Inc. is a worldwide pharmaceutical business based in New York City, New York, with research headquarters in Groton, Connecticut. It is one of the world's most profitable pharmaceutical corporations.

Pfizer is a pharmaceutical company that discovers and manufactures medications and vaccines for a variety of medical fields, including immunology, cancer, cardiology, diabetes/endocrinology, and neurology. Pfizer's products include the cholesterol-lowering drug Lipitor (atorvastatin), Lyrica (pregabalin for neuralgia/fibromyalgia), Diflucan (fluconazole), an oral antifungal, Zithromax (azithromycin), an antibiotic, Viagra (sildenafil, for erectile dysfunction), and Celebrex/Celebroxib (celecoxib), an anti-inflammatory drug, etc.

Pfizer fell to third place in the rankings despite being the leading COVID-19 vaccine maker in North America. The corporation has recently gained traction, particularly in the last quarter, with revenues of $19.0 billion in Q2'2021, representing an 86 percent increase over 2020.

Country: USA

Market Cap Value: $219.39 Billion

Website: https://www.pfizer.com/

Facebook: https://www.facebook.com/Pfizer

Eli Lilly and Company (LLY) is an American pharmaceutical company with locations in 18 countries and a headquarters in Indianapolis, Indiana. It sells its goods in over 125 countries. Colonel Eli Lilly, a pharmaceutical chemist and American Civil War veteran, started the corporation in 1876.

Lilly's major accomplishments include becoming the first company to mass-produce Jonas Salk's polio vaccine and insulin. It was one of the first pharmaceutical companies to use recombinant DNA to make human insulin, including Humulin (insulin medicine), Humalog (insulin lispro), and Basaglar, the first biosimilar insulin product licensed in the United States (insulin glargine). Lilly produces all of Prozac (fluoxetine), Dolophine (methadone), Cymbalta (duloxetine), and Zyprexa, which are all produced by Lilly, which is presently the largest maker of psychiatric drugs (olanzapine).

In the 2019 Fortune 500, the company is ranked 123rd. It is ranked 221st on Forbes' Global 2000 list of the world's largest public firms and 252nd on Forbes' America's Best Employers list.

Country: USA
Market Cap Value: $208.99 Billion

Website: https://www.lilly.com/

Facebook: https://www.facebook.com/elilillyandco

Novartis International AG is a Swiss multinational pharmaceutical corporation headquartered in Basel, Switzerland. It is one of the largest pharmaceutical companies by both market capitalization and sales. Novartis manufactures clozapine, diclofenac, carbamazepine, valsartan, etc.

Novartis, Switzerland's second-largest pharmaceutical corporation, has been the face of the pharmaceutical business for over 25 years. In 2020, the principal maker of the most well-known pharmaceuticals on the market brought in more than $48 billion in revenue, up 3% from 2019. Novartis AG also holds a 33.3% stake in Roche. However, it does not control Roche. Novartis also owned 24.9% of Idenix Pharmaceuticals prior to its sale to Merck & Co., Inc.

Country: Switzerland

Market Cap Value: $207.70 Billion

Website: https://www.novartis.com/

Facebook: https://www.facebook.com/novartis/?ref=page_internal

AbbVie is a publicly traded biopharmaceutical firm based in the United States that was created in 2013. Abbott Laboratories founded it as a spin-off. TeneoOne and its lead chemical, TNB-383B, were acquired by Abbvie in June 2021. The compound is a BCMA-targeting immunotherapeutic for relapsed or refractory multiple myeloma.

Despite substantial success by their main competitor in the sector, Vertex, AbbVie remains committed to product development in the cystic fibrosis illness area as of 2019. and expects to lower emissions by 25% by 2025 from a base year of 2015. AbbVie announced plans to evaluate the Kaletra/Aluvia HIV medication as a potential COVID-19 treatment in March 2020. To explore the medication's efficacy, the business formed numerous agreements with health authorities in other nations. However, the medicine was shown to be ineffective in treating severe COVID-19 in the first non-blinded, randomized trial.

Country: USA
Market Cap Value: $202.60 Billion

Website: https://www.abbvie.com/

Facebook: https://www.facebook.com/AbbVieGlobal

Merck & Co., Inc., often known as Merck Sharp & Dohme (MSD), is a multinational pharmaceutical business based in Kenilworth, New Jersey. The Merck family formed the Merck Group in Germany in 1668, and the corporation is named after them. In 1891, Merck & Co. established a branch in the United States.

Drugs, vaccines, biological therapies, and animal health products are all developed by the company. In 2020, the business had six medications with revenues of more than one billion dollars each: Keytruda (pembrolizumab) is a cloned antibody used in cancer immunotherapy. (sitagliptin), an anti-diabetic medication used to treat type 2 diabetes. Gardasil, an HPV vaccine. Varivax is a chickenpox vaccine that protects against the disease. Pneumovax 23, a pneumococcal polysaccharide vaccine, is given in conjunction with Bridion (Sugammadex), a neuromuscular blocking medication, and Pneumovax 24, another pneumococcal polysaccharide vaccine.

The company was ranked 69th on the Fortune 500 and 92nd on the Forbes Global 2000 in 2021.

Country: USA

Market Cap Value: $191.67 Billion
Website: https://www.merck.com/

Instagram: https://www.instagram.com/merck/

Novo Nordisk A/S is a Danish multinational pharmaceutical company headquartered in Bagsvaerd, Denmark, with production facilities in eight countries and branches or offices in five countries.

The focus of Novo is on major chronic diseases, which affect hundreds of millions of people and are among the world's most pressing health issues. They develop daring ideas into life-saving and preventive medications by combining company innovation and commercial expertise, as well as insights from patients and partners. To continue to improve the development of medical equipment and digital health solutions, the firm makes long-term investments in novel treatments and technology, including curative stem cell-based therapies. ( refer: Novo Nordisk )

In March, Novo volunteers began testing samples for SARS-CoV-2 with RT-qPCR equipment in the ongoing coronavirus pandemic to increase available test capacity. In June, the business announced it would acquire AstraZeneca spin-off Corvidia Therapeutics for an initial sum of $725 million (up to a performance-related maximum of $2.1 billion), boosting its presence in cardiovascular diseases. In November, the company announced it would acquire Emisphere Technologies for $1.8 billion, gaining control of a pill-based treatment for diabetes. In December, Novo announced it would acquire Emisphere Technologies for $1.35 billion.

Country: Denmark
Market Cap Value: $187.83 Billion

Website: https://www.novonordisk.com/

AstraZeneca plc is an Anglo-Swedish multinational pharmaceutical and biopharmaceutical company with headquarters in Cambridge, England. Its R & D centers are concentrated in Cambridge, Gaithersburg, Maryland, and Molndal, Sweden.

Since 2020, the whole world has suffered severe consequences due to COVID-19. And AstraZeneca's COVID-19 vaccine is more than 89% effective in protecting people against the causative agent of COVID-19, based on clinical studies.

Recent data from Public Health England (PHE) demonstrates that two doses of AstraZeneca's COVID-19 vaccine are 92% effective in reducing hospital admissions due to the Delta variant and show no cases. There were no deaths among those who received the vaccine.

COVID-19 vaccine Astrazeneca is a vaccine used to protect people 18 years of age and older against COVID-19. The vaccine helps the immune system of the vaccinated person to recognize and destroy the coronavirus (SARS-COV-2). This is the virus that causes COVID-19 disease, which causes some patients to become severe and possibly fatal.

Country: UK

Market Cap Value: $152.28 Billion

Website: https://www.astrazeneca.com/

Facebook: https://www.facebook.com/astrazenecacareers

Bristol-Myers Squibb is a global biopharmaceutical firm specializing in the discovery, development, and delivery of novel medications for patients suffering from critical illnesses. Their treatments are benefiting millions of patients throughout the world in illness categories like oncology, cardiology, immunoscience, fibrosis, and others.

The firm also promotes health equity and works to improve the health outcomes of communities impacted by significant diseases and conditions through the Bristol-Myers Squibb Foundation, giving new hope to the world's most vulnerable people. Every day, their employees all around the world working together for their patients gives humanity so much significance and responsibility.

BMS is one of the world's major pharmaceutical businesses, regularly appearing on the Fortune 500 list of the world's most powerful corporations. It generated total sales of $39.3 billion as of September 2020.

Country: USA

Market Cap Value: $145.80 Billion

Website: https://www.bms.com/

Facebook: https://www.facebook.com/BristolMyersSquibb