Interactions
When used with amitriptyline, drugs that interact with it may lessen its effect, shorten its duration of action, exacerbate adverse effects, or have no effect at all. Even while it is not always necessary to cease taking one of the drugs, sometimes there is an interaction between two drugs. Consult your doctor to learn how to handle drug interactions.
Medication interactions with amitriptyline frequently occur and include:
- Warfarin and other blood-thinning medications like aspirin and NSAIDs are examples of anticoagulants (blood thinners).
- Anticonvulsants like phenytoin, phenobarbital, and primidone are examples of anticoagulants (blood thinners).
- Atypical antipsychotics (such as olanzapine, quetiapine, and ziprasidone) and antipsychotics (such as butyrophenones, phenothiazines, or thioxanthenes) as well as antipsychotics (such as butyrophenones, phenothiazines, or thioxanthenes) that may cause drowsiness include benzodiazepines (such as codeine, morphine)
- aspirin
- bupropion
- buspirone
- cimetidine
- cisapride
- diuretics, such as furosemide
- disulfiram
- ipratropium
- lithium
