Precautions and contraindications before taking

Before taking Imbruvica, as with any prescribed medication, it is critical to learn as much as possible about it. Your healthcare provider and pharmacist will provide you with important prescription information. When you first start taking this medication, pay attention to how you feel, and don't be afraid to seek help if anything seems off.

The good news is that Imbruvica has no contraindications, which means that there are no medical conditions that would preclude its use. However, taking other medications may impair Imbruvica's effectiveness. Notably, for MCL and MZL, this drug is only prescribed after all other treatments have failed.

Imbruvica may not be safe to take in certain circumstances, such as the following:

• Pregnancy
• Breastfeeding
• Heart disease
• Pediatric
• Liver problems

You must give your healthcare professional as much information as you can about your health situation.

Imbruvica belongs to a class of drugs known as kinase inhibitors. These inhibit the production of kinase, a protein linked to cancer development and immune response. There are numerous kinase inhibitors, which are classified according to their mode of action. The most notable are type I kinase inhibitors, which work by binding to active forms of kinase, and type II (of which Imbruvica is the first discovered compound). A variety of kinase inhibitors may be indicated for cancer treatment. In addition to Imbruvica, these include:

• Bosulif (bosutinib)
• Iressa (gefitinib)
• Jakafi (ruxolitinib)
• Sprycel (dasatinib)
• Sutent (sunitinib)
• Tarceva (erlotinib)
• Tykerb (lapatinib)
• Votrient (pazopanib)
• Xalkori (crizotinib)
• Zelboraf (vemurafenib)