Side Effects

To ensure that every prescription is effective, regular monitoring is necessary. Tell your healthcare practitioner right away if you're experiencing any side effects if you're taking this medicine. Remain careful; get medical help right away if you experience any serious adverse effects.

Imbruvica, like any pharmaceutical drug, can cause a variety of side effects. These are the most common:

• Diarrhea
• Tiredness
• Muscle and bone pain
• Rash
• Bruising
• Mouth sores (stomatitis)
• Muscle spasms
• Nausea
• Pneumonia

More severe adverse effects occasionally manifest. These are a few of them.

• Hemorrhage: Though relatively uncommon, severe bleeding events have been reported with this drug, occurring in up to 6% of cases. Notably, use has been linked to intracranial hemorrhage, gastrointestinal bleeding, blood in the urine (hematuria), and post-operative hemorrhage (excessive bleeding during and after surgery). Less severe bleeding occurs in 39% of Imbruvica users and is characterized by the presence of red welts or dots on the skin (petechiae) or easier bruising.
• Infection: In 21% of patients, the use of this medication has also been connected to certain viral, fungal, or bacterial illnesses. In particular, the viral infection known as progressive multifocal leukoencephalopathy, which affects the white matter of the brain, is worrisome. Pneumocystis jirovecii pneumonia, a serious fungal lung infection, may also develop.
• Cytopenias: Cytopenia is a condition in which one or more of your blood cell types are lower than normal. Reduced white blood cell levels, as with neutropenia or anemia, in which the body does not get enough oxygen due to a lack of healthy red blood cells, are especially concerning.
• Atrial Fibrillation: Imbruvica increases the possibility of abnormal heartbeats in those with atrial fibrillation and atrial flutter, among other diseases. This is especially dangerous for people with a history of heart disease, high blood pressure, or those who have this condition.
• Hypertension: About 19% of Imbruvica users have high blood pressure. Other medications may be required to help with this.
• Second Primary Malignancies: While you're on this medication, some other conditions and cancers could develop. Non-melanoma skin cancer is the most prevalent of these problems, which are thought to be present in 10% of cases.
• Tumor Lysis Syndrome: Tumor lysis syndrome is a rare condition seen in Imbruvica users in which tumors release their cells into the bloodstream, causing a variety of symptoms such as nausea, muscle cramping, vomiting, diarrhea, and fatigue.
• Embryo-Fetal Toxicity: Imbruvica may harm a growing fetus, according to research conducted on animals. The relative benefits and hazards of using this medication while pregnant are carefully weighed by healthcare professionals, who will also inform you of any risks.