Stomach Pain and Diarrhea
Typically, stomach discomfort and diarrhea coexist with nausea and vomiting. Approximately 40% of participants in a 2021 review on zinc supplementation for the common cold complained of gastrointestinal pain and diarrhea. Although less common, gastrointestinal discomfort and bleeding might occur.
An individual developed intestinal hemorrhage after using 220 mg of zinc sulfate twice a day to treat acne in one case study. Although zinc chloride is not included in supplements, accidental intake of household goods can result in poisoning. Zinc chloride is found in adhesives, sealants, soldering fluxes, cleaning solvents, and wood finishing products.