Tips

Entresto is typically administered twice daily. It is safe to take with or without food.

Any signs or symptoms of angioedema (swelling of the face or throat, difficulty breathing) should be reported to your doctor right away.

May cause a drop in blood pressure that manifests as light-headedness; consult your doctor for guidance; symptoms usually resolve with continued therapy. Take care not to become dehydrated.

Do not use potassium-containing salt substitutes without first consulting your doctor.

Entresto is typically used in conjunction with other medications to lower blood pressure, and you should abide by all dietary and lifestyle advice given to you by your doctor (such as losing weight if overweight, quitting smoking, engaging in regular exercise, and limiting your sodium intake). In addition, other conditions need to be managed, such as high cholesterol or diabetes if present.

Do not take any additional medications, including those purchased over-the-counter, unless your doctor or pharmacist has confirmed that they are safe to take with Entresto.