Upsides

Cosentyx may be used to treat adults and children over the age of six with moderate to severe plaque psoriasis who require systemic therapy or phototherapy.

Cosentyx may also be used to treat active psoriatic arthritis in adults, adolescents, and children aged 2 and up, as well as enthesitis-related arthritis in adults and children aged 4 and up.

Adults with active ankylosing spondylitis and active non-radiographic axial spondyloarthritis (nr-axSpA) with objective signs of inflammation may also benefit from Cosentyx. Cosentyx may be used for conditions other than rheumatoid arthritis.

Cosentyx reduces inflammation by inhibiting the release of proinflammatory cytokines and chemokines.

Cosentyx is usually given once a month by subcutaneous injection after an initial loading dose (which for plaque psoriasis consists of 300mg doses of Cosentyx given every week for five doses) (under the skin). Cosentyx is typically administered in 300mg doses (two injections), but some patients may only require a 150mg dose.

Cosentyx is typically administered in 150mg doses, with or without loading doses, for other conditions. If there is no response, higher doses may be administered.

Cosentyx comes in three forms: a Sensoready pen, a prefilled syringe, and lyophilized powder in a vial for reconstitution. The lyophilized powder for reconstitution is only for use by healthcare providers.

A healthcare professional can teach people who have been prescribed Cosentyx how to self-administer the Sensoready pen or prefilled syringe.

Although Cosentyx has few side effects, it may increase the risk of infection.