Upsides

Relieves moderate-to-severe acute and chronic pain that other pain relievers are unable to control.

Hydrocodone (alone) is only available in abuse-deterrent, branded, extended-release forms marketed as Hysingla ER, Vantrela ER, and Zohydro ER.

It has a lower risk of constipation, nausea, and vomiting than morphine. Hydrocodone, on the other hand, may be more constipating than oxycodone.

Those at increased risk of opiate overdosage or who have household members, including children, at risk of accidental ingestion or overdosage, may be prescribed with naloxone.

Hydrocodone is available in combination with other medications, such as acetaminophen and hydrocodone, and ibuprofen and hydrocodone. These combination medications are available in generic form.