Depression
Chronic or long-term stress can have negative effects, typically it can also worsen depression, a mood disorder that makes you feel down and disinterested in things you find enjoyable. Your sleep patterns, concentration, and appetite can all be affected by depression.
Excessive stress can result in major depression in people who are susceptible to the condition. Chronic stress may wear you down and make you feel overwhelmed when you struggle to handle challenging life situations. This is a result of fluctuating hormone levels, including cortisol, dopamine, and serotonin, which cause a prolonged stress response that can cause depression. Stress-related neglect of a healthy lifestyle, such as excessive drinking and lack of exercise, can also raise the risk of serious depression.