Autologous Bone Marrow Transplant

To continue, Toplist would like to introduce to you Autologous Bone Marrow Transplant. In the case of autologous BMT, ex vivo procedures such as cytotoxic drug treatment, exposure to monoclonal antibodies that attack tumor-associated antigens, or harvesting and introducing stem cells (cells from peripheral blood) are used to destroy the malignant cells in the patient's marrow prior to reinfusion.

In the treatment of severe lupus, autologous bone marrow transplantation (ABMT) has been tried. In 2011, an international evaluation of ABMT in more than 200 adult patients with refractory disease revealed a 50% to 70% remission rate at 5 years, but a significant early mortality rate must be addressed through improved patient selection, induction, maintenance, and long-term patient follow-up. There have been reports of allogenic bone marrow transplantation and allogenic bone marrow mesenchymal stem cell transplantation being successful in adult SLE patients. Today, Autologous Bone Marrow Transplant is among the most expensive medical procedures at $410,000.

Cost: $410,000