Interactions

Medicines that interact with Zubsolv may reduce its impact, shorten its duration of action, enhance adverse effects, or have no effect when combined. An interaction between two drugs may not necessarily necessitate the discontinuation of one of them; nonetheless, it can. Consult your doctor about how to handle medication interactions.


Zubsolv may interact with the following medications:

  • 5-hydroxytryptophan
  • albuterol
  • antibiotics, such as azithromycin, clarithromycin, erythromycin, and norfloxacin
  • antidepressants, such as tricyclic antidepressants (eg, amitriptyline), monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine), or SSRIs (eg, fluoxetine, sertraline)
  • antifungal agents, such as itraconazole and ketoconazole
  • anticonvulsants, such as brivaracetam, carbamazepine, divalproex, lamotrigine, phenytoin, phenobarbital, or primidone
  • antipsychotics (such as butyrophenones, phenothiazines, or thioxanthenes) and atypical antipsychotics (eg, aripiprazole, olanzapine, quetiapine, ziprasidone)
  • any medication that may cause drowsiness, such as benzodiazepines (eg, alprazolam, diazepam, lorazepam), sleeping pills (such as zolpidem or ziprasidone), or first-generation antihistamines (such as doxylamine or promethazine)
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