May reduce inflammation

Ashwagandha includes chemicals, such as WA, that may aid in the reduction of inflammation in the body. WA has been discovered to target inflammatory pathways in the body, including signal molecules known as nuclear factor kappa B (NF-B) and nuclear factor erythroid 2-related factor 2 (NF-ERF2) (Nrf2). WA has been proven in animal experiments to help lower levels of inflammatory proteins such as interleukin-10 (IL-10). Ashwagandha may also help lower inflammatory indicators in people, according to some data.

Adults experiencing stress were given ashwagandha extract for 60 days in one 2008 trial. As a result, individuals had much lower levels of C-reactive protein, an inflammatory marker, as compared to those who received a placebo. In another study, patients with COVID-19 were given an Ayurvedic medication including 0.5 grams of ashwagandha and other herbs twice daily for 7 days. When compared to a placebo, this reduced individuals' levels of inflammatory markers CRP, IL-6, and TNF-.