How does Invokana work?
Top 3 in Top 8 Things to Know About Invokana
A hormone called insulin isn't working properly or you're not producing enough of it if you have Type 2 diabetes. Your body uses insulin to metabolize glucose (sugar). Insufficient insulin can cause blood glucose levels to rise. If their glucose levels continue to be elevated, people with diabetes can experience a variety of health issues.
As was already stated, Invokana belongs to a class of drugs known as SGLT2 inhibitors. Invokana (Canagliflozin) functions by preventing the sodium-glucose co-transporter 2 (SGLT2) from carrying glucose from the blood that passes through the kidneys (the glomerular filtrate) back into circulation. SGLT2 is a protein found in the early proximal tubule of a nephron or kidney cell. Canagliflozin stops glucose from being reabsorbed and increases the amount of glucose excreted in the urine by blocking this transporter. This lowers blood sugar and raises A1C.
But Invokana does more than just reduce blood sugar levels. Additionally, it stops sodium from returning to circulation. This reduces kidney pressure, which can eventually harm them in higher levels.