What is Invokana used for?

Invokana is only approved by the FDA for people with Type 2 diabetes. When combined with a healthy diet and exercise, it can help lower your blood sugar.

However, Invokana has other applications. It has been shown to reduce the risk of certain people's heart problems worsening. Invokana has been approved by the Food and Drug Administration to reduce the risk of heart attack, stroke, and even death in people with Type 2 diabetes and heart disease.

Invokana can help people whose kidney disease is caused by diabetes (diabetic nephropathy) and protein in their urine from getting worse. Invokana is FDA-approved for people with this type of kidney disease to reduce the risk of:

• Worsening kidney disease
• Death due to heart problems
• Being hospitalized for heart failure

Even though Invokana is only FDA-approved for people with Type 2 diabetes, the American College of Cardiology and American Heart Association both recommend an SGLT2 inhibitor for some people with heart failure, regardless of whether they have diabetes. This is an off-label use of Invokana, but it is supported by substantial clinical evidence.